amfast is a new remoting library  that looks to be as sweet as pyamf (where sweet == fast and useful).  I am checking out amfast now but the speed boost alone might be worth it.  For instance, working with real-time games, when you need static content you need to grab that quickly sometimes via a content service.  The faster that link the better. It also has Twisted integration which is great for networking and SQLAlchemy integration which is in my opinion the best ORM for python (pyamf has twisted, django, pylons, sqlalchemy as well)

amfast is well documented and has some great examples.  If you have the Python addiction, check it.

Description

• AmFast is a Flash remoting framework for Python.
• AmFast can use AMF to communicate between Python and Flash, Flex, and any other system that supports AMF.
• AMF is a binary object serialization protocol used by Actionscript based applications.

Server Features

• Support for NetConnection and RemoteObject RPC.
• Support for Producer/Consumer ‘push’ messaging with HTTP polling, HTTP long-polling, and real-time HTTP streaming channels.
• Support for authentication with NetConnection and RemoteObject.
• Flexible Target mapping system to map message destinations to invokable Target objects.
• Support for ChannelSets with multiple Channels to expose resources in different ways.
• Built in Channels for CherryPy, Twisted Web, and plain WSGI.
• Support for configurable Endpoints. Use AmFast’s built-in AMF encoder/decoder C-extension, or use an external AMF encoder/decoder, such as PyAmf for a pure-Python implementation.

AMF Encoder/Decoder Features

• AMF0/AMF3 encoder/decoder written in C as a Python extension for speed.
• More than 10x faster than the PyAmf encoder/decoder (even when using PyAmf’s optional C-extension).
• Map custom classes with ClassDef objects for complete control over serialization/de-serialization.
• Full support for IExternalizable objects.
• Data persistence with SqlAlchemy including remotely-loadable lazy-loaded attributes.
• Actionscript code generation from ClassDef objects.

Features of pyAMF currently:

• AMF0 encoder/decoder for legacy Flash Players (version 6-8).
• AMF3 encoder/decoder for the new AMF format in Flash Player 9.
• Support for IExternalizable, ArrayCollection, ObjectProxy, ByteArray (with zlib support), RecordSet and RemoteObject
• Remoting gateways for Twisted, Django, TurboGears2, Web2Py, Pylons and any compatible WSGI framework.
• Authentication/setCredentials support
• Remoting client using httplib with authentication support
• Service Browser (DescribeService header) requests supported
• Local Shared Object (LSO) support
• Adapter Framework to integrate nicely with third-party Python projects

More on the PyAMF library:

• Download — Download PyAMF
• Examples — Tutorials and examples
• Features — PyAMF features
• Documentation – General documentation
• Mailing List — Join the mailinglist for user and developer discussions
• Blog — Announcements and news
• IRC Channel — Chat and discuss PyAMF or get support
• Success Stories — See how PyAMF is being used
• Team — The people working on this project
• License — The project is licensed under the open source MIT license

Haxe has a similar premise where it can compile to Flash6-9 versions of actionscript 2-3 which makes for a system with better reach. Python code for this is lots of fun and very flexible. Python is becoming a baseplane language and one great language for transcending platform lock-in.

Check out this snippet pulled from here (click to see sample game)

#/usr/bin/env python
"""
This simple example has very little to do with the pygame
chimp example, except that it will act the same (more or less)
and it uses the same resources, only they got converted to
mp3s, pngs.
"""
 
#Import Modules
from pypy.translator.flex.modules.flex import *
 
class MyRect:
    def __init__(self,x,y,w,h):
        self.x, self.y,self.w,self.h = x,y,w,h
 
SCREEN_W = 468
SCREEN_H = 60
 
class Game:
    def __init__(self):pass
 
    def init(self,screen):
        self.screen = screen
        screen.layout = 'absolute'
        screen.setActualSize(SCREEN_W, SCREEN_H)
 
        screen.addEventListener('mouseMove',mousemotion)
        screen.addEventListener('enterFrame',do_loop)
        screen.addEventListener('click',chimp_whip)
 
        self.bg = load_sprite("py_background_png");
        self.screen.addChild(self.bg)
 
        self.chimp = load_sprite("py_chimp_png");
        self.screen.addChild(self.chimp)
 
        self.orig_y = self.chimp.y
 
        img2 = self.fist = load_sprite("py_fist_png")
        self.screen.addChild(img2)
        img2.move(400,img2.height/2)
        self.move = 1
        self.spin = 0
        self.hit = 0
        self.hit_move = 1
 
        self.sfx = {}
        self.sfx['whip'] = load_sound_resource("py_punch_mp3")
        self.sfx['nohit'] = load_sound_resource("py_whiff_mp3")
 
    def loop(self):
        img = self.chimp
        if self.spin:
            self.spin -= 1
            img.rotation = self.spin*24
        else:
            img.x += self.move * 8
            if img.x > SCREEN_W-img.width:
                self.move = -1
            if img.x < 0:
                self.move = 1
 
        if self.hit:
            self.hit -= 1
            self.fist.y += 6 * self.hit_move
 
            if self.hit  SCREEN_W - img_halfw:
        newx = SCREEN_W - img.width
    if newx  img.x and e.stageX < img.x+img.width:
        game.sfx['whip'].play()
        game.spin = 20
    else:
        game.sfx['nohit'].play()
 
def flash_main( x=1 ):
    game.init(castToWindow(x))